File:Putting Phage to Work — Interspecies Immunology (50433409786).png
![File:Putting Phage to Work — Interspecies Immunology (50433409786).png](https://upload.wikimedia.org/wikipedia/commons/thumb/e/ea/Putting_Phage_to_Work_%E2%80%94_Interspecies_Immunology_%2850433409786%29.png/800px-Putting_Phage_to_Work_%E2%80%94_Interspecies_Immunology_%2850433409786%29.png?20210510085112)
Original file (2,080 × 1,178 pixels, file size: 825 KB, MIME type: image/png)
Captions
Captions
Summary
[edit]DescriptionPutting Phage to Work — Interspecies Immunology (50433409786).png |
Congrats to Sensei Bio on their $28M Series AA financing with the Cambrian Bio investors, including Future Ventures. Sensei reengineers the common bacteriophage (the cool one that looks like an alien lunar lander) to expose the unique antigen signatures of tough human cancers. The viral capsid is both a cheaply-manufactured nanoparticle and a natural adjuvant for a complete, effective and safe vaccine (the phage cannot infect human cells and are inactivated). They are currently in Phase 2 clinical trials for Head and Neck Cancer and have shown broader applicability for infectious diseases. Phage are incredible workhorses in the natural world, killing half of all bacteria on Earth every 48 hours. Their replication cycle in bacteria affords rapid and inexpensive mass manufacturing. Company: <a href="https://senseibio.com" rel="noreferrer nofollow">senseibio.com</a> Today's <a href="https://www.businesswire.com/news/home/20201007005938/en/Sensei-Biotherapeutics-Announces-28.5-Million-Financing-To-Advance-Clinical-Pipeline-and-Immunophage%e2%84%a2-Platform-Targeting-Multiple-Cancers" rel="noreferrer nofollow">news</a>. And from a separate <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971447/" rel="noreferrer nofollow">U.S. gov't paper</a>: "Phages offer many unique features useful when aiming to develop a robust inflammatory immune response targeted at viral infection or cancer. Phage‐based vaccines, like other nanotechnologies, aim to present antigen to the immune system while simultaneously activating stimulatory pathways. Phages specifically have been used in a wide array of applications ranging from biosensors to cancer immunotherapies. Reasons for this diversity include the ability to produce a large number of viral particles in a rapid and cost‐effective manner, advantageous sizes and aspect ratios, the ability to display proteins and peptides in highly‐ordered arrays, and phage safety profile in humans. Of specific interest to vaccines and immunotherapies, phages have demonstrated an ability to activate both the innate and adaptive immune systems. The combination of both the innate and adaptive immune pathways is crucial in generating robust and long‐lasting antigen‐specific responses." |
Date | |
Source | Putting Phage to Work — Interspecies Immunology |
Author | Steve Jurvetson from Los Altos, USA |
Licensing
[edit]![w:en:Creative Commons](https://upload.wikimedia.org/wikipedia/commons/thumb/7/79/CC_some_rights_reserved.svg/90px-CC_some_rights_reserved.svg.png)
![attribution](https://upload.wikimedia.org/wikipedia/commons/thumb/1/11/Cc-by_new_white.svg/24px-Cc-by_new_white.svg.png)
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
![]() |
This image was originally posted to Flickr by jurvetson at https://flickr.com/photos/44124348109@N01/50433409786. It was reviewed on 10 May 2021 by FlickreviewR 2 and was confirmed to be licensed under the terms of the cc-by-2.0. |
10 May 2021
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 08:51, 10 May 2021 | ![]() | 2,080 × 1,178 (825 KB) | Sentinel user (talk | contribs) | Transferred from Flickr via #flickr2commons |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Horizontal resolution | 56.69 dpc |
---|---|
Vertical resolution | 56.69 dpc |