File:Proposed model for human embryogenesis with amnion as an organizer.png
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| Description | FIG. 4. Colocalization of 3,3′-diaminobenzidine (DAB)-stained visceral endoderm and Spink3+/Ttr+/Trh+ endoderm in E7.5 embryos. E7.5 mouse embryo showing the distribution of DAB+ endoderm alone (A) and colocalization of DAB+ and Spink3+ endoderm (B). Sagittal (C, D) and coronal (E, F) sections of a double stained E7.5 mouse embryo. The position of Spink3+ DAB− cells is bracketed by arrowheads in D and F. An E7.5 mouse embryo showing the colocalization of DAB+ and Trh+ endoderm in wholemount (G), sagittal (H, I), and coronal (J, K) sections. The border between the Trh+ cells and DAB+ cells is indicated by the arrowheads. An E7.5 mouse embryo showing the colocalization of DAB+ and Ttr+ endoderm in wholemount (L), sagittal (M, N), and coronal (O, P) sections. The position of Ttr+ DAB− cells is bracketed by arrowheads in N and P. The dashed line indicates the position of the embryonic and extra-embryonic boundary in all images. *Anterior. |
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| Source | https://www.liebertpub.com/doi/10.1089/biores.2014.0010#supplementary-materials Hwee Ngee Goh, Peter D. Rathjen, Mary Familari, and Joy Rathjen BioResearch Open Access Vol. 3, No. 3. Endoderm Complexity in the Mouse Gastrula Is Revealed Through the Expression of Spink3 https://doi.org/10.1089/biores.2014.0010 |
| Author | Hwee Ngee Goh, Peter D. Rathjen, Mary Familari, and Joy Rathjen |
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© 2022, Ávila-González et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.
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| current | 00:10, 6 September 2024 | | 1,219 × 972 (616 KB) | Rasbak (talk | contribs) | {{Information |description=Proposed model for human embryogenesis with amnion as an organizer.<br> Simplified scheme of embryonic stages in humans and its in vitro counterparts of human pluripotent stem cell lines (hPSC) represent or possess some characteristics of each state. Totipotency can be represented by the expanded and extended hPSC (1). Different conditions to maintaining naïve hPSC have been characterized, which resemble the pre-implantation epiblast (2). The formative pluripotency... |
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