File:Prolactin pone.0101403.g003.png

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Original file (3,246 × 4,151 pixels, file size: 3.57 MB, MIME type: image/png)

Captions

Captions

Add a one-line explanation of what this file represents

Summary

[edit]
Description Figure 3. Effects of in vivo treatment with fadrozole on the cellular proliferation of prolactin-positive cells. a) Double labelled immunohistochemistry for prolactin (dark blue-grey) and PCNA (brown). In untreated animals, few prolactin-positive cells are labelled for PCNA (arrow). Scale bar: 12 µm. b) After 5 doses of fadrozole it is uncommon to find cells labelled jointly for PCNA and prolactin (arrow points to PCNA- but not prolactin-positive cells). Scale bar: 12 µm. c) The percentage of prolactin-positive cells decreases significantly with respect to the untreated or control animals after 1 dose (**p<0.01 with respect to untreated animals, and p<0.05 with respect to control animals) or 5 doses (**p<0.01 with respect to untreated and control animals and p<0.05 with respect to 1 dose of the fadrozole treated animals). After 1 dose of saline the percentage decreases with respect to untreated animals (#p<0.05), but not after 5 doses. d) Fadrozole decreases the proliferation of prolactin-positive cells (*p<0.05 with respect to untreated and control animals; **p<0.01 with respect to untreated and control animals and p<0.05 with respect to 1 dose of fadrozole-treated animals).
Date
Source https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101403 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101403 Local Transformations of Androgens into Estradiol by Aromatase P450 Is Involved in the Regulation of Prolactin and the Proliferation of Pituitary Prolactin-Positive Cells
Author María José García Barrado, Enrique J. Blanco, Marta Carretero Hernández, María Carmen Iglesias Osma, Manuel Carretero, Julio J. Herrero, Deborah Jane Burks, José Carretero

Open access

Licensing

[edit]
w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

DNA-binding proteins

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current10:24, 8 January 2024Thumbnail for version as of 10:24, 8 January 20243,246 × 4,151 (3.57 MB)Rasbak (talk | contribs){{Information |description=Figure 3. Effects of in vivo treatment with fadrozole on the cellular proliferation of prolactin-positive cells. a) Double labelled immunohistochemistry for prolactin (dark blue-grey) and PCNA (brown). In untreated animals, few prolactin-positive cells are labelled for PCNA (arrow). Scale bar: 12 µm. b) After 5 doses of fadrozole it is uncommon to find cells labelled jointly for PCNA and prolactin (arrow points to PCNA- but not prolactin-positive cells). Scale bar:...

You cannot overwrite this file.

There are no pages that use this file.

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:Prolactin_pone.0101403.g003.png&oldid=839573594"