File:Profile of intense and punctate reelin IR during hippocampal maturation journal pone 0005505 g001.png

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English: Figure 1. Profile of intense and punctate reelin IR during hippocampal maturation. (A) Bins of average fluorescent intensities detected in somata of 12 div hippocampal neurons immunostained for reelin (n = 380 neurons). Intensities ranging from 100 to 4030 were divided into 110 bins and the number of somata was counted within each bin. The vertical lines mark the threshold values used to identify the different reelin-positive populations (1450 and 2650). (B) Top: Representative image of somatic reelin immunoreactivities found in 12 div hippocampal neurons. Bottom: reelin immunofluorescence (red) overlaid with MAP2 counterstain (green). Neurons with intense and punctate reelin IR are present in the same field as neurons with no detectable reelin IR. (C, D) Expression profiles between 6 and 21 div, of intense (C, P<0.001: ***versus 6 and 8 div, ΔΔ versus 21 div) and punctate reelin IR (D, P<0.01: **versus 6 div, Δ versus 8 div). Bar graphs represent the average percentage±sem of reelin-positive neurons within the total number of neuronal somata counted on the corresponding phase-contrast images. High magnification images of 12 div neurons displaying intense (C) or punctate reelin IR (D) are shown on the top. Images were taken from the same coverslip with identical exposure times.
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Source Reelin Secreted by GABAergic Neurons Regulates Glutamate Receptor Homeostasis - PLoS ONE, 2009
Author Campo CG, Sinagra M, Verrier D, Manzoni OJ, Chavis P
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w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 2.5 Generic license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

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current04:55, 13 May 2009Thumbnail for version as of 04:55, 13 May 20091,502 × 1,589 (625 KB)CopperKettle (talk | contribs){{Information |Description={{en|1=Figure 1. Profile of intense and punctate reelin IR during hippocampal maturation. (A) Bins of average fluorescent intensities detected in somata of 12 div hippocampal neurons immunostained for reelin (n = 380 neurons).

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