File:Profile of intense and punctate reelin IR during hippocampal maturation journal pone 0005505 g001.png
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[edit]DescriptionProfile of intense and punctate reelin IR during hippocampal maturation journal pone 0005505 g001.png |
English: Figure 1. Profile of intense and punctate reelin IR during hippocampal maturation.
(A) Bins of average fluorescent intensities detected in somata of 12 div hippocampal neurons immunostained for reelin (n = 380 neurons). Intensities ranging from 100 to 4030 were divided into 110 bins and the number of somata was counted within each bin. The vertical lines mark the threshold values used to identify the different reelin-positive populations (1450 and 2650). (B) Top: Representative image of somatic reelin immunoreactivities found in 12 div hippocampal neurons. Bottom: reelin immunofluorescence (red) overlaid with MAP2 counterstain (green). Neurons with intense and punctate reelin IR are present in the same field as neurons with no detectable reelin IR. (C, D) Expression profiles between 6 and 21 div, of intense (C, P<0.001: ***versus 6 and 8 div, ΔΔ versus 21 div) and punctate reelin IR (D, P<0.01: **versus 6 div, Δ versus 8 div). Bar graphs represent the average percentage±sem of reelin-positive neurons within the total number of neuronal somata counted on the corresponding phase-contrast images. High magnification images of 12 div neurons displaying intense (C) or punctate reelin IR (D) are shown on the top. Images were taken from the same coverslip with identical exposure times. |
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Date | |||
Source | Reelin Secreted by GABAergic Neurons Regulates Glutamate Receptor Homeostasis - PLoS ONE, 2009 | ||
Author | Campo CG, Sinagra M, Verrier D, Manzoni OJ, Chavis P | ||
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current | 04:55, 13 May 2009 | 1,502 × 1,589 (625 KB) | CopperKettle (talk | contribs) | {{Information |Description={{en|1=Figure 1. Profile of intense and punctate reelin IR during hippocampal maturation. (A) Bins of average fluorescent intensities detected in somata of 12 div hippocampal neurons immunostained for reelin (n = 380 neurons). |
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