File:Plasma proteomic organ aging models versus established clinical markers of aging, health, and disease.webp
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From the study "Organ aging signatures in the plasma proteome track health and disease"
Summary
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| Description |
English: "a, Phenotypic Age (PhenoAge, Levine et al. 2018) was calculated based on 10 clinical markers in the Covance cohort (n = 1,026). PhenoAge-based age prediction is shown. b, The PhenoAge age gap was calculated and correlated with plasma proteomic organ aging model age gaps. Pairwise correlations are shown. c, Organ age gaps and the PhenoAge age gap were associated with 43 individual clinical markers of health and disease. Phenotype covariate effect sizes and significance based on Benjamini Hochberg FDR corrected p-values for all associations are shown. Asterisks represent q-value thresholds: *q < 0.05; **q < 0.01; ***q < 0.001. (See ST14)."
It is one of the studies briefly featured in 2023 in science |
| Date | |
| Source | https://www.nature.com/articles/s41586-023-06802-1 |
| Author | Authors of the study: Hamilton Se-Hwee Oh, Jarod Rutledge, Daniel Nachun, Róbert Pálovics, Olamide Abiose, Patricia Moran-Losada, Divya Channappa, Deniz Yagmur Urey, Kate Kim, Yun Ju Sung, Lihua Wang, Jigyasha Timsina, Dan Western, Menghan Liu, Pat Kohlfeld, John Budde, Edward N. Wilson, Yann Guen, Taylor M. Maurer, Michael Haney, Andrew C. Yang, Zihuai He, Michael D. Greicius, Katrin I. Andreasson, Sanish Sathyan, Erica F. Weiss, Sofiya Milman, Nir Barzilai, Carlos Cruchaga, Anthony D. Wagner, Elizabeth Mormino, Benoit Lehallier, Victor W. Henderson, Frank M. Longo, Stephen B. Montgomery & Tony Wyss-Coray |
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 13:37, 5 March 2024 | | 2,016 × 1,952 (289 KB) | Prototyperspective (talk | contribs) | Uploaded a work by Authors of the study: Hamilton Se-Hwee Oh, Jarod Rutledge, Daniel Nachun, Róbert Pálovics, Olamide Abiose, Patricia Moran-Losada, Divya Channappa, Deniz Yagmur Urey, Kate Kim, Yun Ju Sung, Lihua Wang, Jigyasha Timsina, Dan Western, Menghan Liu, Pat Kohlfeld, John Budde, Edward N. Wilson, Yann Guen, Taylor M. Maurer, Michael Haney, Andrew C. Yang, Zihuai He, Michael D. Greicius, Katrin I. Andreasson, Sanish Sathyan, Erica F. Weiss, Sofiya Milman, Nir Barzilai, Carlos Cruchag... |
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