File:Planar cell polarity in tubular morphogenesis.jpg
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| Description | Figure 2. Planar cell polarity in tubular morphogenesis. Deletion of core PCP proteins from vertebrates results in defects in tubular morphogenesis during development. PCP mutant tubules are dilated (A); a phenotype which may occur due to defects in two planar-polarised behaviours. The first is convergent extension, defects in which have been inferred based on the increased number of epithelial cells per tubular cross-section (B) and consequently a reduction in tubular elongation (C). The second planar-polarised behaviour which is impaired in these models is the orientation of cell division and, in kidneys with disruption of core PCP components, this deviates from the plane of the tubule (D). |
| Date | |
| Source | https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2021.599529/full#ack1 The Biological Significance and Implications of Planar Cell Polarity for Nephrology. Front. Physiol. 12:599529. doi: 10.3389/fphys.2021.599529 |
| Author | Papakrivopoulou E, Jafree DJ, Dean CH and Long DA |
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© 2021 Papakrivopoulou, Jafree, Dean and Long. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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| current | 10:11, 27 May 2024 | | 2,266 × 3,068 (578 KB) | Rasbak (talk | contribs) | {{Information |description=Figure 2. Planar cell polarity in tubular morphogenesis. Deletion of core PCP proteins from vertebrates results in defects in tubular morphogenesis during development. PCP mutant tubules are dilated (A); a phenotype which may occur due to defects in two planar-polarised behaviours. The first is convergent extension, defects in which have been inferred based on the increased number of epithelial cells per tubular cross-section (B) and consequently a reduction in tubu... |
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