File:On the Action of Cobra Venom. Parts I and II (1918) (14581452639).jpg

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Identifier: philtrans08247806 (find matches)
Title: On the Action of Cobra Venom. Parts I and II
Year: 1918 (1910s)
Authors: Cushny, A. Yagi, S.
Subjects: Proceedings of the Royal Society of London Philosophical Transactions of the Royal Society
Publisher: Royal Society of London

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se per pressure. i 30 sec. min. sec. min. sec. mm. Hg. 0 0 to 0 30 148 98 0 30 1 0 146 96 2 mgrm. per kgrm. venom intravenously. 1 0 1 30 146-124 94 I 30 2 0 124-40-47 67 2 0 2 30 47-42 79 2 30 3 0 42-39 86 3 0 3 30 39-42 84 o 30 4 0 42-80 85 4 0 4 30 82-58 49 4 30 5 0 58 56 26 5 0 6 0 56-68 35 6 0 7 0 68-76 44 7 0 8 0 76-82 50 8 0 9 0 82-80 49 9 0 10 0 80-86 52 10 .0 18 0 86-88 83 18 0 28 0 88-74 94 28 0 43 0 74-64 95 43 0 45 0 64-50 93 45 0 55 0 50-0 i E 2 28 PROF. A. E. CUSHNY AND DR. S. YAGI Experiment 4,—^A cat weighing 2-5 kgrm. was ansesthetised with veronal and kept under artificialrespiration. Time. Blood Pulse per pressure. 30 sec. mill. sec. mill. sec. mm. Hg. 0 0 to 0 30 101 101 i 0 30 1 0 101-94 100 2 mgrm. per kgrm. intravenously. j 1 0 1 30 97-41 83 1 30 2 0 41-18 37 2 0 2 30 18-36 41 2 30 3 0 36-47 45 j . B 0 3 30 47-49 44 3 30 4 0 48 46 4 0 5 0 46 46 5. 0 6 0 46 46 6 0 7 0 46-59 65 - 7- 0 8 0 59-64 84 8 0 9 0 64 51 81 9 0 10 0 51-20 92 10 0 11 0 20-13 11 0 12 b 13-0
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Fig. 5.~-Blood pressure of an atropinised cat under artificial respiration before and after the injection of2 mgrm. venom P per kgrm. at the point indicated on the signal line. Time in sec. Intervalbetween a and h is 5 min.; between h and c, 3 min.; between c and d, 9 min.; between d and e,20 min.; between e and/, 6 min. My observations lead me to ascribe the changes in the heart and blood pressurealmost entirely to direct action on the heart and vessels, the inhibitory mechanism notbeing markedly influenced, and the asphyxia only playing an important part in the ON THE ACTION OF COBEA VENOM. 29 later stages. Direct observation of the heart in situ or perfused with Ringer showsthat the rate of the heart is slowed and its strength and tone ai*e increased undersmall quantities of venom. In a more advanced stage, however, the heart dilates lessand less fully, so that the output gradually diminishes. In the intact animal small quantities of venom at first cause a slight rise of theblood p

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https://www.flickr.com/photos/internetarchivebookimages/14581452639/

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Cushny, A.;

Yagi, S.
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Flickr tags
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  • bookid:philtrans08247806
  • bookyear:1918
  • bookdecade:1910
  • bookcentury:1900
  • bookauthor:Cushny__A_
  • bookauthor:Yagi__S_
  • booksubject:Proceedings_of_the_Royal_Society_of_London
  • booksubject:Philosophical_Transactions_of_the_Royal_Society
  • bookpublisher:Royal_Society_of_London
  • bookcontributor:
  • booksponsor:
  • bookleafnumber:27
  • bookcollection:philosophicaltransactions
  • bookcollection:additional_collections
Flickr posted date
InfoField
28 July 2014



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