File:Negative Node from Mastectomy Specimen; Cytokeratin Immunostain with Expression of Chromogen by Mast Cells (6959258321).jpg
![File:Negative Node from Mastectomy Specimen; Cytokeratin Immunostain with Expression of Chromogen by Mast Cells (6959258321).jpg](https://upload.wikimedia.org/wikipedia/commons/thumb/8/89/Negative_Node_from_Mastectomy_Specimen%3B_Cytokeratin_Immunostain_with_Expression_of_Chromogen_by_Mast_Cells_%286959258321%29.jpg/600px-Negative_Node_from_Mastectomy_Specimen%3B_Cytokeratin_Immunostain_with_Expression_of_Chromogen_by_Mast_Cells_%286959258321%29.jpg?20131211121057)
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[edit]DescriptionNegative Node from Mastectomy Specimen; Cytokeratin Immunostain with Expression of Chromogen by Mast Cells (6959258321).jpg |
Lobular carcinomas are so cytologically bland that they present devilish problems with false-negative biopsies. However, false-positives can also be a problem, as shown in this node, which could be misinterpreted as keratin-positive cells in the medullary sinus, thus a false-positive for isolated tumor cells (ITC). In fact, these are benign mast cells that have converted the chromogen in the absence of any antibody-antigen or avidin-biotin reaction. |
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Author | Ed Uthman from Houston, TX, USA |
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This image, originally posted to Flickr, was reviewed on 11 December 2013 by the administrator or reviewer File Upload Bot (Magnus Manske), who confirmed that it was available on Flickr under the stated license on that date. |
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current | 12:10, 11 December 2013 | ![]() | 1,426 × 1,425 (529 KB) | File Upload Bot (Magnus Manske) (talk | contribs) | Transferred from Flickr by User:CFCF |
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Camera manufacturer | NIKON |
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Camera model | E995 |
Exposure time | 10/1,909 sec (0.0052383446830801) |
F-number | f/3.3 |
ISO speed rating | 100 |
Date and time of data generation | Unknown date |
Lens focal length | 8.2 mm |
Horizontal resolution | 300 dpi |
Vertical resolution | 300 dpi |
Software used | E995v1.6 |
File change date and time | Unknown date |
Y and C positioning | Co-sited |
Exposure Program | Normal program |
Exif version | 2.1 |
Date and time of digitizing | Unknown date |
Meaning of each component |
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Image compression mode | 2 |
APEX exposure bias | 0 |
Maximum land aperture | 0 APEX (f/1) |
Metering mode | Pattern |
Light source | Unknown |
Flash | Flash did not fire |
Supported Flashpix version | 1 |
Color space | sRGB |
File source | Digital still camera |
Scene type | A directly photographed image |
Unique image ID | f6269a3b86d57878a10feace9e97efca |