File:NOGO-A expression during cell migration.jpg
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English: NOGO-A expression during cell migration. A) H&E staining of optic tectum at HH30(E7) showing the generative zone (GZ), the migrating zone (MZ) and the first neuronal lamina (L1). B) Section in situ hybridization (sISH) of NOGO-A in an adjacent section demonstrating a corresponding radial pattern of expression in the region of migration. High magnification of the MZ (from boxed region in "A") shows the elongated processes of radial glia and associated migrating neurons. C) H&E for morphologic comparison; D) vimentin (Vim) immunohistochemistry (IHC) decorating the intermediate filaments of the radial glia; E) IHC of Neurofilament (NF) targeting migrating neurons; and F) sISH showing NOGO-A expression (red) more closely resembling NF staining. Scale bar 200 μm in A, B; 50 μm in C, D, E, F.
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| Date | |
| Source | NOGO-A induction and localization during chick brain development indicate a role disparate from neurite outgrowth inhibition |
| Author | Caltharp SA, Pira CU, Mishima N, Youngdale EN, McNeill DS, Liwnicz BH, Oberg KC |
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© 2007 Caltharp et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Other versions | Derivative works of this file: HE stain murine optic tectum.jpg |
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| current | 10:11, 11 July 2009 | | 1,200 × 605 (395 KB) | CopperKettle (talk | contribs) | {{Information |Description={{en|1=NOGO-A expression during cell migration. A) H&E staining of optic tectum at HH30(E7) showing the generative zone (GZ), the migrating zone (MZ) and the first neuronal lamina (L1). B) Section in situ hybridization (sISH) of |
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