File:Melanoma (6).jpg

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Description
English:
Title Melanoma
Description The patient is a 53 year old woman with metastatic melanoma to multiple subcutaneous sites and retroperitoneum. She was treated with tumor infiltrating lymphocytes (TILs) transduced with the gene for tumor necrosis factor (TNF). Pretreatment biopsy shows multiple live melanoma cells with little lymphoid infiltrate. Following treatment with TNF gene modified TILs plus interleukin-2, a biopsy of another lesion showed massive coagulative necrosis of the tumor with no viable tumor seen. This is a typical picture seen in experimental animals treated with tumor necrosis factor. This patient has had a substantial objective response that is currently ongoing at nine months following initiation of treatment. For additional resource, see the following web site: http://www.cancer.gov/cancertopics/wyntk/moles-and-dysplastic nevi See also http://www.cancer.gov/cancertopics/wyntk/melanoma.
Topics/Categories Cancer Types -- Melanoma Treatment -- Experimental Therapy
Type Color, Photo
Source Dr. Steven Rosenberg
Date
Source
This image was released by the National Cancer Institute, an agency part of the National Institutes of Health, with the ID 2561 (image) (next).

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Author Unknown photographer
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(Reusing this file)		 Reuse Restrictions None - This image is in the public domain and can be freely reused. Please credit the source and/or author listed above.

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Public domain This image is a work of the National Institutes of Health, part of the United States Department of Health and Human Services, taken or made as part of an employee's official duties. As a work of the U.S. federal government, the image is in the public domain.
Please ensure that this image was actually created by the US Federal government. The NIH frequently uses commercial images which are not public domain.
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current13:41, 21 January 2013Thumbnail for version as of 13:41, 21 January 20132,331 × 1,800 (2.04 MB)Fæ (talk | contribs){{Information |Description = {{en|<br> :'''Title''' Melanoma :'''Description''' The patient is a 53 year old woman with metastatic melanoma to multiple subcutaneous sites and retroperitoneum. She was treated with tumor infiltrating lymphocytes (TILs) t...

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