File:Medical diseases of infancy and childhood (1900) (14764275744).jpg

English: Fig. [on left] represents a girl, Theophilia P., aged two years, admitted to the Johns Hopkins Hospital, December 18, 1895. Mother a Pole, no goiter in the family. Child presents the typical aspect of infantile myxedema. The thyroid gland can be felt and seems a little large. She can neither sit nor stand; is pale, the skin of the face having a sallow waxy appearance. Tongue is large and held out all the time. The expression of the face is dull and idiotic. Puffiness and myxedematous character of the skin of both hands and face. The head measures 45 cm. in circumference, 25½ cm, 11 in. the transverse, and 35 cm. in the anterior-posterior. The anterior fontanelle is large, almost as much so as at birth. Child's length on admission was 65 cm. The blood-count gave 4,648,000 red corpuscles, 80 per cent, of hemoglobin, and about 11,000 leukocytes. On December 20th she was placed on the thyroid extract prepared by Dr. Abel. On beginning the treatment she weighed twenty pounds. Within two months, as illustrated in Fig. [at right], the condition improved remarkably. She took an interest in surrounding objects. The eyes had become bright and intelligent ; the puffiness of the face and hands had almost wholly gone. As shown in the photograph, the palpebral orifices [relating to the eyelids] had become much larger. The tongue was not held out so far from the month, and the drooling had almost ceased. She remained in the hospital until September 1, 1896. The myxedematous condition disappeared entirely, she gained eight pounds in weight, and had thriven in every way. It is interesting to note in this case that from March 20th to April 4th, the child received no thyroid extract. She had had a little fever and bronchitis, and it was stopped. On the latter date it was noticed that the skin had become harsh and dry, the eyelids more puffy, and the child did not seem nearly so well.

Identifier: medicaldiseaseso00will (find matches)
Title: Medical diseases of infancy and childhood
Year: 1900 (1900s)
Authors: Williams, Dawson, 1854- (from old catalog) Churchill, Frank Spooner, 1864- (from old catalog) ed
Subjects: Children
Publisher: Philadelphia and New York, Lea brothers & co.
Contributing Library: The Library of Congress
Digitizing Sponsor: The Library of Congress

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ncrease and to cause much aching pain inthe part. This may be to some extent combated by gymnastic ex-ercises, but other bony deformities may occur, due to thickening and CBETINISM. 263 softening—apparently of a rickety nature—of the bones of the ex-tremities ^ (Fig- -T). It may therefore be necessary to keep thepatient recumbent, and even to apply splints for some months, whilethe effect of the treatment by thyroid is producing its maximumeffect. (Osiers series of cretins illustrate so well the characteristic ap-pearance of the condition and especially the effects of thyroid treat-ment that it is reproduced here. Fig. 30 presents a typicalpicture of a sporadic cretin, aged seventeen years, under the careof Dr. J. C. Caisson, of Syracuse, New York. Fig. 30 was takena vear before treatment and Fig. 31 illustrates the condition a yearat\er. Fig. 32 represents a girl, Theophilia P., aged two years, admittedto the Johns Hopkins Hospital, December 18, 1895. Mother a Fig. 32. Fig. 33. b
Text Appearing After Image:
Pole, no goitre in the family. Child presents the typical aspect ofinfantile myxredema. The thyroid gland can be felt and seems alittle large. She can neither sit nor stand; is pale, the skin of theface having a sallow waxy appearance. Tongue is large and heldout all the time. The expression of the face is dull and idiotic.Puffiness and myxcedematous character of the skin of both hands See a paper by Dr. .John Thomson, Brit. Med. Jour., 189G, vol. ii., p. G18, andthe discuaeion thereon. Osier : loc. cit. 264 DISEASES OF THE THYROID AND THYMUS GLANDS. and face. The head measures 45 cm. in circumference, 25J cm, 11in the transverse, and 35 cm. in the antero-posterior. The an-terior fontanelle is large, almost as much so as at birth. Childs Fig. 34.

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