File:Mallory body high mag cropped.jpg

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Original file (1,118 × 1,216 pixels, file size: 473 KB, MIME type: image/jpeg)

Captions

Captions

mallory body

Summary

[edit]
Description
English: High magnification micrograph of a Mallory body, as seen in steatohepatitis. Liver biopsy. H&E stain.

Mallory bodies are eosinophilic cytoplasmic inclusions that are aggregates of denatured keratin filaments. They have a twisted rope-like appearance. On trichrome stain they are green/dark brown.

Associations (histologic):

  • They often have neutrophils around them.
  • They frequently are seen in hepatocytes undergoing ballooning degeneration.

Deutsch: Starke mikroskopische Vergrösserung eines Mallory Körperchens, welches als solches in einer Steatohepatitis verkommt. Leberbiopsie. Hämatoxylin-Eosin-Färbung.

Mallory Körper sind eosinophile, zytoplasmatische Einschlüsse, wobei es sich um Aggregate von denaturierten Keratinfilamenten handelt. Sie erscheinen in ihrem Äusseren wie gewundene Stränge. In der trichromatischen Färbung sind sie grün/dunkel braun.

Prevalence and associations

They are classically found in the livers of people suffering from alcoholic liver disease and were once thought to be specific for that.

They are most common in alcoholic hepatitis (prevalence of 65%) and alcoholic cirrhosis (prevalence of 51%).

They are a recognized feature of Wilson's disease (25%), primary biliary cirrhosis (24%), non-alcoholic cirrhosis (24%), hepatocellular carcinoma (23%) and morbid obesity (8%), among other conditions.

See also

Source Own work
Author Nephron

Licensing

[edit]
I, the copyright holder of this work, hereby publish it under the following licenses:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
GNU head Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled GNU Free Documentation License.
You may select the license of your choice.
Annotations
InfoField
This image is annotated: View the annotations at Commons

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current02:43, 15 September 2009Thumbnail for version as of 02:43, 15 September 20091,118 × 1,216 (473 KB)Nephron (talk | contribs){{Information |Description={{en|1=High magnification micrograph of a '''Mallory body''', as seen in steatohepatitis. Liver biopsy. H&E stain. Mallory bodie

The following 2 pages use this file:

File usage on other wikis

The following other wikis use this file:

Metadata