File:Limb-representation patterns in the deprived cortex reflect usage.jpg

English: Limb-representation patterns in the deprived cortex reflect usage—whole brain contrasts. (A) Coloured lines delineate the boundaries of clusters activated during execution of movements using the feet (green), arms (blue), hands (white), and lips (pink) in controls, projected on inflated hemispheres. (B) Whole-brain group comparisons for activation during residual/nondominant arm movements (in 1-handed/control participants, respectively; deprived hemisphere is in front. Note that participants with above elbow deprivation were excluded). During movements of the residual arm, the congenital group showed increased activation compared with the acquired and control groups. This whole-brain contrast resulted in a single cluster, centred on the hand knob of the central sulcus of the deprived cortex, spanning the pre- and post-central gyri (shown in orange). (C) Whole-brain group comparisons for activation during intact/dominant hand movements (in 1-handed/control participants, respectively). During movements of the intact hand, the acquired group showed increased activation compared with the conjunction of the congenital and control groups. This whole-brain contrast resulted in a single cluster centred on the hand knob of the deprived cortex spanning the pre- and post-central gyri (shown in orange). The square inserts in (B and C) show overlap between the clusters resulting from the whole brain group comparisons (orange) and the controls’ hand area (white), as shown in (A). No other significant clusters were identified here, or using the homologous contrasts between the other groups.