File:Kinase inactive 002.png
From Wikimedia Commons, the free media repository
Jump to navigation
Jump to search
Size of this preview: 800 × 379 pixels. Other resolutions: 320 × 152 pixels | 640 × 303 pixels | 1,398 × 662 pixels.
Original file (1,398 × 662 pixels, file size: 366 KB, MIME type: image/png)
File information
Structured data
Captions
Summary
[edit]DescriptionKinase inactive 002.png |
English: (left) Ribbon diagram of the x-ray crystal structure of c-Kit kinase in complex with Imatinib (PDB id: 1T46): In the middle between the two lobes, there is the type-II inhibitor Imatinib (carbons in green). (right) Overview of the imatinib binding with (inactive/“DFG-out” conformation), highlighting regions that are relevant for small molecule inhibitor binding: A, adenine binding site/linker region; R, ribose binding region; P, phosphate binding region occupied by DFG motif; Br_I, extended back hydrophobic binding region after changing the orientation of the DFG motif; Br_II, front specificity binding region. Br_III, additional binding region in the allosteric site, used for solubilizing groups in type-II kinase inhibitors. |
Date | |
Source | Own work |
Author | Chaos |
Licensing
[edit]I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 11:20, 18 March 2024 | 1,398 × 662 (366 KB) | Chaos (talk | contribs) | Uploaded own work with UploadWizard |
You cannot overwrite this file.
File usage on Commons
The following page uses this file:
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Software used |
---|
Hidden categories: