File:Josso Loop.svg

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Deutsch: Der Tissue-Faktor (TF, III) und Proconvertin (VII) aktivieren nicht nur Thrombokinase (X), sondern auch Serinprotease (IX). Die ersten kleinen Mengen Thrombin (II) aktivieren nicht nur Fibrin (I), sondern auch den Faktor (VIII). Der aus VIII und IX gebildete Tenasekomplex aktiviert wiederum die Thrombokinase (X), so dass sich eine sich selbst verstärkende Schleife bildet. Dieser wichtige Schritt wird auch als Josso-Loop bezeichnet. Nach F. Josso, O. Prou-Wartelle: Interaction of tissue factor and factor VII at the earliest phase of coagulation. In: Thrombosis et diathesis haemorrhagica. Supplementum. Band 17, 1965, ISSN 0375-9997, S. 35–44, PMID 5874847.
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current14:56, 1 February 2015Thumbnail for version as of 14:56, 1 February 2015416 × 506 (53 KB)A1b2 commons (talk | contribs)background crop
14:52, 1 February 2015Thumbnail for version as of 14:52, 1 February 2015744 × 1,052 (61 KB)A1b2 commons (talk | contribs)User created page with UploadWizard

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