File:Interstate medical journal (1919) (14760949261).jpg

Identifier: interstatemedica2619unse (find matches)
Title: Interstate medical journal
Year: 1919 (1910s)
Authors:
Subjects: Medicine
Publisher: St. Louis, : Interstate Medical Journal
Contributing Library: The College of Physicians of Philadelphia Historical Medical Library
Digitizing Sponsor: The College of Physicians of Philadelphia and the National Endowment for the Humanities

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theperiphery in the direction of the distal end of the nerve; if thedistance is too great to span, then lateral offshoots are sent outfrom neighboring nerves. iS. Walter Ranson (Journal of Comparative Neurology, 1912, XXII, p. 487). Warner: False Neuromas in Amputation Stumps 143 The axones are always sent out from the central stump in thedirection of the distal end, and it is from the central stump thatregeneration finally takes place. Even if the distance betweenproximal and distal stumps are very considerable, Ranson hasshown, by means of a new stain, that the new intervening connectivetissue is no bar to the axone penetration of it. If the distance isvery great, he found in his experiments that offshoots from lateralnerves penetrated the intervening connective tissue in an effort atbridging the two ends of the severed nerve with new axis cylinders.It has not been possible to demonstrate the method of this regenera-tion until the technic of Cajal, with his new stain, and quoted by
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Section of the terminal enlarged end of the tibial nerve showing the abortivefibrils formed of connective tissue derived from the neurellemma in theprocess of incomplete regeneration of nerve tissue. The form of the fibrils ispreserved during the process of abortive regeneration. Ranson, was brought to the attention of neurological researchworkers. Where the distal stump of the nerve is completely removed fromthe body, as in amputations, it is interesting to note what an effortnature makes in some cases to regenerate the central stump soas to reach the distal end of the severed nerve with new axones.The following case is of interest in this line: - M. J. P., aged 63, had his left leg amputated in 1884 by reasonof an accident. Twenty years later, in 1904, he was operated uponfor the removal of a bulbar enlargement of the end of one of thenerves in the stump. Just how long this enlargement had been 144 INTERSTATE MEDICAL JOURNAL present he does not know, but the stump had been painful f

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