File:HMB synthesis historical.svg
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[edit]DescriptionHMB synthesis historical.svg |
English: Synthetic routes to β-hydroxy β-methylbutyric acid.
The first reported chemical syntheses of HMB were: the oxidation of 2-methylpent-4-en-2-ol with chromic acid (H2CrO4) in 1877 by the Russian chemists Michael and Alexander Zaytsev;[1] the oxidative cleavage of 4-methylpentane-1,2,4-triol with potassium permanganate (KMnO4) in 1880 and 1889 by Schirokoff and Reformatsky, respectively;[2][3] and, the oxidation with permanganate of 3-methylbutane-1,3-diol in 1892 by Kondakow.[4]
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Author | Boghog |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 04:48, 27 March 2018 | 609 × 208 (48 KB) | DMacks (talk | contribs) | more standard to write chromic acid as "H2CrO4" than "CrO4H2" | |
06:17, 6 November 2016 | 609 × 208 (48 KB) | Boghog (talk | contribs) | User created page with UploadWizard |
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