File:Genomic hairs Nature mars 2016 cc-by-sa4 graph fr.jpg
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[edit]DescriptionGenomic hairs Nature mars 2016 cc-by-sa4 graph fr.jpg |
Français : En haut de l'image sont présentés des dessins illustrant les sept caractéristiques des cheveux examinés dans l'échantillon de l'étude CANDELA. Les lignes épaisses et colorées relient ces caractéristiques avec les gènes candidats identifiés(Tableau 1 ).
dans le bas, un graphe composite affichant tous les polymorphismes nucléotidiques (SNP en anglais, pour single-nucleotide polymorphism) associés de manière significative pour les caractères du système pileux examinés. Le nombre rs du polymorphisme nucléotidique (chiffre vertical) avec la plus petite valeur de P est affiché en haut de chaque pic d'association (cf. tableau 1 ; indice de polymorphismes nucléotidiques). Schéma publié dans une étude des génomes de plus de 6000 personnes sud-américaines dont les ancêtres étaient amérindiens, africains ou européens, et portant sur les liens entre génétique et certains éléments du système pileux. A cette occasion un gène très probablement responsable de la synophridie a été récemment découvert au sein d’un groupe de 18 gènes impliqués dans la production, la forme et l'épaisseur du cheveux, du sourcil et du poil de barbe. Ce travail a été publié en open data/open source (cc-by-sa 4.0) dans Nature Communications le 1er mars 2016 (Kaustubh Adhikari & al. (2016) A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features, Nature Communications 7, art n°10815, doi:10.1038/ncomms10815).English: At the top are shown drawings illustrating the seven hair features examined in the CANDELA study sample. Thick lines connect these features with the candidate genes identified in regions with SNPs reaching genome-wide significant association (Table 1). At the bottom is shown a composite Manhattan plot displaying all significantly associated SNPs for the hair features examined. The rs number of the SNP with the smallest P value is shown at the top of each association peak (Table 1 index SNP). |
Date | |
Source | Kaustubh Adhikari & al. (2016) A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features, Nature Communications 7, art n°10815, doi:10.1038/ncomms10815 (cc-by-sa 4.0) |
Author | Kaustubh Adhikari & al. |
source : Nature Communications ; 01 03 2016 : (Kaustubh Adhikari & al. (2016) A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features, Nature Communications 7, art n°10815, doi:10.1038/ncomms10815). cc-by-sa 4.0
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File change date and time | 21:35, 5 March 2016 |
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Date and time of digitizing | 19:31, 5 March 2016 |
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