File:Fst of Brazilians and Mexicans - Distribution.png

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English: Distribution of FST values. Pairwise comparisons were done for the three ancestral populations and for the admixed populations Mexico and Brazil, a) Europe vs Africa; b) Europe vs Native American; c) Africa vs Native American; and d) Mexico vs Brazil. The figure shows the distribution of FST values for all the pairwise comparisons in a graphical format. The average FST values are low, indicating reduced genetic differentiation. However, it is important to note the broad distribution of FST values. While most of the genetic markers have low genetic differentiation, there are many outliers with high FST values. The highest average FST values are observed between the African and the Native American samples (FST = 0.085). The FST values observed for the African-European and European-Native American comparisons were 0.059 and 0.062, respectively. The average genetic differentiation between the Brazilian and Mexican samples with respect to the parental samples is lower than the genetic differentiation observed between the parental samples (FST = 0.012), as expected given the history of admixture in Brazil and Mexico.
Date Published: November 24, 2014
Source Bonifaz-Peña V, Contreras AV, Struchiner CJ, Roela RA, Furuya-Mazzotti TK, Chammas R, et al. (2014) Exploring the Distribution of Genetic Markers of Pharmacogenomics Relevance in Brazilian and Mexican Populations. PLoS ONE 9(11): e112640. doi:10.1371/journal.pone.0112640 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112640
Author Vania Bonifaz-Peña, Alejandra V. Contreras, Claudio Jose Struchiner, Rosimeire A. Roela, Tatiane K. Furuya-Mazzotti, Roger Chammas, Claudia Rangel-Escareño, Laura Uribe-Figueroa, María José Gómez-Vázquez, Howard L. McLeod, Alfredo Hidalgo-Miranda, Esteban J. Parra , Juan Carlos Fernández-López , Guilherme Suarez-Kurtz
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