File:FragileX.png

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Description
English: Silencing of the FMR1 Gene in Fragile X Mental Retardation Syndrome: Artistic representation of events occurring during gene silencing in Fragile X mental retardation syndrome (FXS). The FMR1 gene, which is on the X chromosome, colocalizes with a fragile site seen in FXS cells that gives this disorder its name. FXS alleles become associated with SIRT1. SIRT1, a class III histone deacetylase, deacetylates lysine 9 of histone H3 and lysine 16 of histone H4, ultimately leading to chromatin compaction and gene silencing (see Biacsi et al., e1000017).
doi:10.1371/image.pgen.v04.i03.g001
Date (UTC)
Source http://www.plosgenetics.org/article/info:doi%2F10.1371%2Fimage.pgen.v04.i03
Author Dr. Marian L. Miller (Journal-Cover-Art.com).
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Other versions http://www.plosgenetics.org/article/slideshow.action?uri=info:doi/10.1371/image.pgen.v04.i03&imageURI=info:doi/10.1371/image.pgen.v04.i03.g001

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The original description page was here. All following user names refer to en.wikipedia.
Date/Time Dimensions User Comment
2010-01-20 16:14 600×600× (300909 bytes) ClockworkSoul {{Information |Description = Silencing of the FMR1 Gene in Fragile X Mental Retardation Syndrome: Artistic representation of events occurring during gene silencing in Fragile X mental retardation syndrome (FXS). The FMR1 gene, which is on the X chromo

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Date/TimeThumbnailDimensionsUserComment
current19:07, 5 August 2014Thumbnail for version as of 19:07, 5 August 2014600 × 600 (294 KB)Mithril (talk | contribs)Transferred from en.wikipedia

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