File:Fneur-10-00574-g001.jpg
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Fneur-10-00574-g001.jpg (765 × 543 pixels, file size: 277 KB, MIME type: image/jpeg)
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[edit]DescriptionFneur-10-00574-g001.jpg |
English: "The bidirectional interplay between the brain and the gut is mediated by neural, such as the vagus nerve (VN-gateway), and humoral pathways, such as the lymphatic tissue and the bloodstream (Non-VN gateways). A monolayer of epithelial cells separates the intestinal lumen and the complex gut microbiome from the underlying lymphoid and enteric nervous tissues. The structure of alpha-synuclein amyloid fibrils (PDB 2N0A) is based on atomic-resolution molecular data from NGL Viewer (19). Members of the gut microbiome and their extracellular compounds may trigger responses in the VN through enteroendocrine cells, which are contacted by vagus nerve terminals through specialized structures called neuropods (NP) (20). Microbial antigens can cross the gut epithelium through microfold cells, playing a central role in localized inflammatory responses [adapted from Bohórquez et al. (21)]. Toll-like receptors are microbe-sensing proteins, present in intestinal epithelial cells, mediating recognition of commensal bacteria from the harmful/inflammatory ones. ENS, enteric nervous system; M, microfold cells; NP, neuropods; PP, Peyer's patches; TLR4, Toll-like receptor 4; VN, vagus nerve." (Santos Susanne Fonseca, de Oliveira Hadassa Loth, Yamada Elizabeth Sumi, Neves Bianca Cruz, Pereira Antonio 2019.) |
Date | |
Source | https://www.frontiersin.org/articles/10.3389/fneur.2019.00574/full |
Author | Santos Susanne Fonseca, de Oliveira Hadassa Loth, Yamada Elizabeth Sumi, Neves Bianca Cruz, Pereira Antonio |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 04:14, 16 November 2021 | 765 × 543 (277 KB) | Thinkpins (talk | contribs) | Uploaded a work by Santos Susanne Fonseca, de Oliveira Hadassa Loth, Yamada Elizabeth Sumi, Neves Bianca Cruz, Pereira Antonio from https://www.frontiersin.org/articles/10.3389/fneur.2019.00574/full with UploadWizard |
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Width | 20,669 px |
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Height | 14,590 px |
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Pixel composition | RGB |
Orientation | Normal |
Number of components | 3 |
Horizontal resolution | 72 dpi |
Vertical resolution | 72 dpi |
Software used | Adobe Photoshop CS6 (Windows) |
File change date and time | 12:16, 3 June 2019 |
Exif version | 2.21 |
Color space | sRGB |
Date and time of digitizing | 21:00, 17 May 2019 |
Date metadata was last modified | 17:46, 3 June 2019 |
Unique ID of original document | 81E1BCABC8BA1335DD3FE1C3D6B2007B |
IIM version | 5,369 |
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