File:Fncel-15-736008-g001.jpg
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Captions
Captions
FBXW7 neurodevelopmental syndrome
Summary
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| Description |
English: FIGURE 1. Schematic illustration of the SCFFBXW7 E3 ubiquitin ligase complex (A) and FBXW7 gene (B) and proteins (C). (A) Functional model of FBXW7 involved in SCF complex-mediated substrate ubiquitylation. Ubiquitin and phosphorylation is indicated with Ub and P with a circle, respectively. (B,C) Alternative transcriptional initiations from different promoters generate three distinct FBXW7 transcripts and corresponding proteins with conserved D, F-box and WD40 repeat domains. All three FBXW7 transcripts (or isoforms) share 10 common exons which were shown with gray rectangles. |
| Date | |
| Source | https://www.frontiersin.org/articles/10.3389/fncel.2021.736008/full |
| Author | Yu Yang, Xuan Zhou, Xinpeng Liu, Ruying Song, Yiming Gao, Shuai Wang |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 22:08, 21 October 2023 | | 2,913 × 1,308 (169 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Yu Yang, Xuan Zhou, Xinpeng Liu, Ruying Song, Yiming Gao, Shuai Wang from https://www.frontiersin.org/articles/10.3389/fncel.2021.736008/full with UploadWizard |
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