File:Fendo-10-00484-g003.jpg

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Captions

Pseudohyperaldosteronism

Summary

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Description
English: FIGURE 3. Red blood cell (RBC) membrane alterations induced by oxidative stress and the possible anti-inflammatory effect of licorice. Glycyrrhetinic acid (GA), which has been shown to directly interact with membrane sphingolipids and cholesterol, can induce a protective shield against membrane protein oxidation, mainly avoiding protein band 3, the main constituents of RBC membranes, from being oxidized by ROS to form high molecular weight aggregate (HMWA), recognized by circulating IgG as premature aged cells. GA also prevents protein glutathionylation, which would avoid cytosolic GSH store depletion and support the correct functioning of cytosolic enzymes such as Carbonic Anhydrase (CA2).
Date
Source https://www.frontiersin.org/articles/10.3389/fendo.2019.00484/full
Author Chiara Sabbadin, Luciana Bordin, Gabriella Donà, Jacopo Manso, Giampiero Avruscio, Decio Armanini

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current22:45, 18 August 2023Thumbnail for version as of 22:45, 18 August 20231,084 × 437 (383 KB)Ozzie10aaaa (talk | contribs)Uploaded a work by Chiara Sabbadin, Luciana Bordin, Gabriella Donà, Jacopo Manso, Giampiero Avruscio, Decio Armanini from https://www.frontiersin.org/articles/10.3389/fendo.2019.00484/full with UploadWizard

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