File:F2.DOI.10.5772.67671.png

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Pathophysiological mechanisms of autoimmune diseases.

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Description
English: Pathophysiological mechanisms of autoimmune diseases. Autoimmune diseases are multifactorial diseases, and their etiologies are not yet fully known. Their development depends on genetic susceptibility, environmental factors, hormonal factors, and immune dysregulation. These factors may influence, according to different mechanisms, the abnormal activation of potentially dangerous autoreactive cells. Other components are involved in enhancing the autoimmune process, including, antigen-presenting cells, inflammatory cells, and many chemical and soluble mediators such as vasoactive amines, nitric oxide, lipid mediators, growth factors, complement system, cytokines, etc. APC, antigen-presenting cell; IC, inflammatory cell; NO, nitric oxide.
Date
Source Mourad Aribi (March 22nd 2017). Introductory Chapter: Immune System Dysfunction and Autoimmune Diseases, Immunopathogenesis and Immune-based Therapy for Selected Autoimmune Disorders, Mourad Aribi, IntechOpen, DOI: 10.5772/67671. Available from: https://www.intechopen.com/chapters/54266
Author Mourad Aribi

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