File:Enoxacin synthesis.svg
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Enoxacin synthesis
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English: Blancafort, P.; Serradell, MN; Mealy, NE; Castaer, J.; Leeson, PA; Drugs Fut1981,6,(3):129.
Matsumoto, Jun-Ichi; Miyamoto, Teruyuki; Minamida, Akira; Nishimura, Yoshiro; Egawa, Hiroshi; Nishimura, Haruki (1984). "Synthesis of fluorinated pyridines by the balz-schiemann reaction. An alternative route to enoxacin, a new antibacterial pyridonecarboxylic acid". Journal of Heterocyclic Chemistry. 21 (3): 673–679. doi:10.1002/jhet.5570210309. Matsumoto, Junichi; Miyamoto, Teruyuki; Minamida, Akira; Nishimura, Yoshiro; Egawa, Hiroshi; Nishimura, Haruki (1984). "1,4-Dihydro-4-oxopyridinecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1,6,7-trisubstituted 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent". Journal of Medicinal Chemistry. 27 (3): 292–301. doi:10.1021/jm00369a011. Jun-ichi Matsumoto, Yoshiyuki Takase, & Yoshiro Nishimura, US4359578 (1982 to Laboratoire Roger Bellon SA, Dainippon Pharmaceutical Co Ltd). Miyamoto, Teruyuki; Egawa, Hiroshi; Matsumoto, Jun-Ichi (1987). "Pyridonecarboxylic acids as antibacterial gaents. VIII. An alternative synthesis of enoxacin via fluoronicotinic acid derivatives". CHEMICAL & PHARMACEUTICAL BULLETIN. 35 (6): 2280–2285. doi:10.1248/cpb.35.2280.Sanchez, Joseph P.; Rogowski, John W. (1987). "An efficient synthesis of 6-fluoronalidixic acid and its conversion to enoxacin". Journal of Heterocyclic Chemistry. 24 (1): 215–217. doi:10.1002/jhet.5570240139. |
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| Source | Own work |
| Author | Nuklear |
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| current | 11:54, 30 December 2022 | | 512 × 164 (45 KB) | Nuklear (talk | contribs) | Uploaded own work with UploadWizard |
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