File:Effets de la sécrétion des différentes cytokines sur la polarisation des T CD4+.jpg

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Effets_de_la_sécrétion_des_différentes_cytokines_sur_la_polarisation_des_T_CD4+.jpg ‎(531 × 355 pixels, file size: 154 KB, MIME type: image/jpeg)

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Français : La polarisation des cellules T CD4 + induit par les cellules dendritiques. Lorsqu'elles sont en contact avec CD , les cellules T CD4 + naïves peuvent se différencier en un certain nombre de sous-types. Parmi eux, se trouvent des sous-ensembles de cellules T régulatrices (Treg) et T auxiliaires (Th), qui incluent les cellules Th1, Th2 et Th17. Chaque sous-type exprime différents facteurs de transcription, qui régulent la sécrétion des cytokines. Ces différentes cytokines vont orienter la sécrétion immunoglobuline G, A , E.
English: . CD4+ T cell fate induced by dendritic cells. When in contact with DC, naïve CD4+ T cells can differentiate into a number of subtypes. Among them, are regulatory T cells (Treg) and T helper (Th) subsets, which include Th1, Th2, and Th17 cells. Each subtype expresses different transcription factors, which regulate the function and cytokine secretion pattern of the cells. The T cell fate decision is a complex phenomenon that heavily depends on the interaction of DC with the T cells and the cytokines present in the microenvironment.
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Source https://www.frontiersin.org/articles/10.3389/fimmu.2018.03176/full
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Patente Thiago A., Pinho Mariana P., Oliveira Aline A., Evangelista Gabriela C. M., Bergami-Santos Patrícia C., Barbuto José A. M. Human Dendritic Cells: Their Heterogeneity and Clinical Application Potential in Cancer Immunotherapy Frontiers in Immunology 19, 2019, 3176

DOI=10.3389/fimmu.2018.03176

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current10:14, 30 April 2020Thumbnail for version as of 10:14, 30 April 2020531 × 355 (154 KB)Mirmillon (talk | contribs)Uploaded a work by Patente Thiago A., Pinho Mariana P., Oliveira Aline A., Evangelista Gabriela C. M., Bergami-Santos Patrícia C., Barbuto José A. M. Human Dendritic Cells: Their Heterogeneity and Clinical Application Potential in Cancer Immunotherapy Frontiers in Immunology 19, 2019, 3176 DOI=10.3389/fimmu.2018.03176 from https://www.frontiersin.org/articles/10.3389/fimmu.2018.03176/full with UploadWizard

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