File:Distinct differentiation pathways for different DA cell groups in mouse.jpg

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Description Figure 4. Distinct differentiation pathways for different DA cell groups in mouse. The localization of the main DA-synthesizing nuclei is shown on a neuromeric representation of the mouse embryonic brain. Signaling molecules and genes known to be involved in the differentiation of the A11 (first row) A8–A10 DA nuclei (in the midbrain and first basal diencephalic prosomeres; second row) and A13 DA nuclei (in the ventral thalamus; third row) are indicated as a table. Note that DA cells in the three different areas depend on different signaling and transcription factors expression at each step of the cell differentiation, although little is still known in the case of A11 and A13. This observation supports the hypothesis that different DA neuronal systems have been recruited independently, by different transcriptional mechanisms, probably early in vertebrate evolution.
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Source https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2011.00021/full Yamamoto K and Vernier P (2011) The evolution of dopamine systems in chordates. Front. Neuroanat. 5:21. doi: 10.3389/fnana.2011.00021
Author Yamamoto K and Vernier P
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© 2011 Yamamoto and Vernier. This is an open-access article subject to an exclusive license agreement between the authors and Frontiers Media SA, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.

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current10:20, 9 September 2024Thumbnail for version as of 10:20, 9 September 20241,235 × 579 (265 KB)Rasbak (talk | contribs){{Information |description=Figure 4. Distinct differentiation pathways for different DA cell groups in mouse. The localization of the main DA-synthesizing nuclei is shown on a neuromeric representation of the mouse embryonic brain. Signaling molecules and genes known to be involved in the differentiation of the A11 (first row) A8–A10 DA nuclei (in the midbrain and first basal diencephalic prosomeres; second row) and A13 DA nuclei (in the ventral thalamus; third row) are indicated as a table....

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