File:Diro SQ LifeCycle lg.jpg
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| Description | Dirofilaria immitis, D. repens, D. tenuis and D. ursi. Various Dirofilaria species of the subgenus Nochtiella can cause subcutaneous infections. During a blood meal, an infected mosquito introduces third-stage filarial larvae of Dirofilaria repens or D. tenuis onto the skin of the definitive host (canids and sometimes felids for D. repens, raccoons for D. tenuis), where they penetrate into the bite wound image . In the definitive host, the L3 larvae undergo two more molts into L4 and adults, the latter of which reside in subcutaneous tissues image . D. repens adult females are usually 100—170 mm long by 460—650 µm wide; males are usually 50—70 mm long by 370—450 µm wide. D. tenuis is slightly smaller; adult females are usually 80-130 mm long by 260—360 µm wide; males are usually 40—50 mm long by 190—260 µm wide. Females produce microfilariae that are released into the peripheral blood image . A mosquito ingests the microfilariae during a blood meal image . After ingestion, the microfilariae migrate from the mosquito’s midgut through the hemocoel to the Malpighian tubules in the abdomen image . There the microfilariae develop into first-stage larvae image and subsequently into third-stage infective larvae image . The third-stage infective larvae migrate to the mosquito’s proboscis image and can infect another definitive host when the mosquito takes a blood meal image . In humans image , D. repens usually manifests as either a wandering worm in the subcutaneous tissue or a granulomatous nodule, although there are reports of pulmonary dirofilariasis with this species. D. tenuis follows a similar presentation, but may also be found around the eye or on the conjunctiva. Because of this, the infection in humans was first known as Dirofilaria conjunctivae. |
| Source | https://www.cdc.gov/dpdx/dirofilariasis/ |
| Author | DPDx is an educational resource designed for health professionals and laboratory scientists. For an overview including prevention, control, and treatment visit www.cdc.gov/parasites/. |
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This work is in the public domain in the United States because it is a work prepared by an officer or employee of the United States Government as part of that person’s official duties under the terms of Title 17, Chapter 1, Section 105 of the US Code.
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https://www.cdc.gov/dpdx/dirofilariasis/, was reviewed on 10 July 2023 by reviewer TheSandDoctor, who confirmed that it was available there under the stated license on that date.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 05:48, 18 September 2019 | | 2,000 × 1,588 (525 KB) | Rasbak (talk | contribs) | {{Information |description=''Dirofilaria immitis'', ''D. repens'', ''D. tenuis'' and ''D. ursi''. Various Dirofilaria species of the subgenus Nochtiella can cause subcutaneous infections. During a blood meal, an infected mosquito introduces third-stage filarial larvae of Dirofilaria repens or D. tenuis onto the skin of the definitive host (canids and sometimes felids for D. repens, raccoons for D. tenuis), where they penetrate into the bite wound image . In the definitive host, the L3 larvae... |
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