File:Decreased proliferation and change in physical properties of mutant optic vesicle.png

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Figure 4. Decreased proliferation and change in physical properties of mutant optic vesicle.

(A) Immunohistochemical analysis for the presence of BrdU-labelled cells in the prospective neural retina on a coronal section of an E10.5 control embryo (left panel) and an Lhx2-Cre:β-cateninflox/flox embryo (right panel). The part of the prospective neural retina that was analysed for BrdU+ cells in the control and mutant embryos are outlined. (B) Immunohistochemical analysis for the presence apoptotic cells as revealed by the presence of activated Casp-3+ cells on coronal section of an E10.5 control embryo (left panel) and a Lhx2-Cre:β-cateninflox/flox embryo (right panel). (C) Immunohistochemical analyses for the presence of phosphorylated myosin light chain 2 (pMLC2) on a coronal section of an E10.5 control embryo. (D) Immunohistochemical analyses for the presence of pMLC2 on a coronal section on an E10.5 Lhx2-Cre:β-cateninflox/flox embryo. Insets in C and D are a magnification of the areas indicated by the squares. Scale bars: (A, B and C, D) 100 µm.
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Source https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081158 Hägglund A-C, Berghard A, Carlsson L (2013) Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation. PLoS ONE 8(12): e81158. https://doi.org/10.1371/journal.pone.0081158
Author Hägglund A-C, Berghard A, Carlsson L
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© 2013 Hägglund et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current20:43, 17 September 2024Thumbnail for version as of 20:43, 17 September 20241,705 × 1,449 (4.23 MB)Rasbak (talk | contribs){{Information |description=Figure 4. Decreased proliferation and change in physical properties of mutant optic vesicle.<br> (A) Immunohistochemical analysis for the presence of BrdU-labelled cells in the prospective neural retina on a coronal section of an E10.5 control embryo (left panel) and an Lhx2-Cre:β-cateninflox/flox embryo (right panel). The part of the prospective neural retina that was analysed for BrdU+ cells in the control and mutant embryos are outlined. (B) Immunohistochemical a...

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