File:Cytoskeleton polarity during notochord development in Ciona.jpg

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Description Figure 2. Cytoskeleton polarity during notochord development in Ciona. (A) F-actin accumulates at the lamellipodium tip, providing migrating forces for cell intercalation. (B) Ventrally accumulated actomyosin contractility provides unbalanced force to drive notochord bending. (C) An actomyosin contractile ring forms at the anterior edge and moves to the equator of notochord cells. Actomyosin ring contraction elongates notochord cells. Microtubules are perpendicular to the AP axis within notochord cells. (D) During lumen expansion, microtubules accumulate at the apical domain, and along with bidirectional migration, they rotate 90° and form oriented bundles toward the leading edges of tractive lamellipodia-like protrusions. An actomyosin contractile ring also exists during lumen expansion and then disappears. At bidirectional migration, F-actin moves to the tip of lamellipodia-like protrusions.
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Source https://www.frontiersin.org/articles/10.3389/fcell.2020.597446/full#S9 Polarity Establishment and Maintenance in Ascidian Notochord. Front. Cell Dev. Biol. 8:597446. doi: 10.3389/fcell.2020.597446
Author Peng H, Qiao R and Dong B
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© 2020 Peng, Qiao and Dong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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current20:35, 26 May 2024Thumbnail for version as of 20:35, 26 May 20242,044 × 2,813 (336 KB)Rasbak (talk | contribs){{Information |description=Figure 2. Cytoskeleton polarity during notochord development in Ciona. (A) F-actin accumulates at the lamellipodium tip, providing migrating forces for cell intercalation. (B) Ventrally accumulated actomyosin contractility provides unbalanced force to drive notochord bending. (C) An actomyosin contractile ring forms at the anterior edge and moves to the equator of notochord cells. Actomyosin ring contraction elongates notochord cells. Microtubules are perpendicular...

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