File:Comparison of lamin A C localization with lamin B1, emerin and chromatin in dysmorphic nuclei of fibroblasts from the subject with HGPS (progeria).jpg
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English: Comparison of lamin A/C localization with lamin B1, emerin and chromatin in dysmorphic nuclei of fibroblasts from the subject with HGPS. Upper panel shows micrographs of fibroblasts from the subject with HGPS labelled with anti-lamin A/C antibodies (a), anti-lamin B1 antibodies (b), the merged signal (c) and DAPI (d). Lower panel shows micrographs of fibroblasts from the same subject labelled with anti-lamin A/C antibodies (e), anti-emerin antibodies (f), the merged signal (g), and DAPI (h). Bar, 10 μm.Paradisi et al. BMC Cell Biology 2005 6:27 doi:10.1186/1471-2121-6-27 |
| Date | |
| Source | Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress |
| Author | Mauro Paradisi , Dayle McClintock , Revekka L Boguslavsky , Christina Pedicelli1 , Howard J Worman and Karima Djabali |
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© 2005 Paradisi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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| current | 15:54, 5 January 2010 | | 1,050 × 441 (46 KB) | CopperKettle (talk | contribs) | {{Information |Description={{en|1=Comparison of lamin A/C localization with lamin B1, emerin and chromatin in dysmorphic nuclei of fibroblasts from the subject with HGPS. Upper panel shows micrographs of fibroblasts from the subject with HGPS labelled wit |
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