File:Cisplatin activation and formation of cisplatin-DNA adducts.png
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| Description | FIGURE 4 Cisplatin activation and formation of cisplatin-DNA adducts (A) Cisplatin is mono-and diaquated upon entering a cell. (B) Cisplatin can form covalent bonds with DNA bases. An intra-strand adduct is formed when cisplatin cross links two bases of the same strand, whereas an inter-strand adduct is formed when cisplatin cross links two bases from different strands. The percentages indicate the frequency of each type of DNA lesion induced by cisplatin (Rocha et al., 2018). |
| Date | |
| Source | https://www.researchgate.net/publication/349921267_Extracellular_Vesicle-Mediated_Chemoresistance_in_Oral_Squamous_Cell_Carcinoma Extracellular Vesicle-Mediated Chemoresistance in Oral Squamous Cell Carcinoma. Front. Mol. Biosci. 8:629888. doi:10.3389/fmolb.2021.629888 Frontiers in Molecular Biosciences www.frontiersin.org March 2021 Volume 8 Article 6298881 REVIEW doi: 10.3389/fmolb.2021.629888 |
| Author | Law ZJ, Khoo XH, Lim PT, Goh BH, Ming LC, Lee WL and Goh HP |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 23:30, 15 May 2024 | | 1,320 × 879 (367 KB) | Rasbak (talk | contribs) | {{Information |description=FIGURE 4 Cisplatin activation and formation of cisplatin-DNA adducts (A) Cisplatin is mono-and diaquated upon entering a cell. (B) Cisplatin can form covalent bonds with DNA bases. An intra-strand adduct is formed when cisplatin cross links two bases of the same strand, whereas an inter-strand adduct is formed when cisplatin cross links two bases from different strands. The percentages indicate the frequency of each type of DNA lesion induced by cisplatin (Rocha et... |
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