File:CelulasRegulHormon.jpg

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Español: FIGURA 1. Regulación hormonal de la homeostasis de la glucosa en las células de los islotes.

Este diagrama ilustra los efectos metabólicos del glucagón y la insulina.
Los niveles de glucosa en sangre influyen en la secreción de insulina y glucagón. La deficiencia de insulina conduce a un aumento de la lipólisis, un aumento de la proteólisis y una disminución de la utilización de la glucosa, mientras que el exceso de glucagón conduce a una disminución de la síntesis de glucógeno, un aumento de la cetogénesis, un aumento de la glucogenólisis y una gluconeogénesis.

Las flechas rojas se refieren a un efecto estimulante, mientras que las flechas azules se refieren a un efecto inhibitorio.
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Role of Glucagon and Its Receptor in the Pathogenesis of Diabetes Front. Endocrinol., 2022

Sec. Diabetes: Molecular Mechanisms
Author Yunbo Jia, Yang Liu, Linlin Feng, Siyu Sun Guangwei Sun

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