File:CRISPR CAS9 technology.png
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[edit]DescriptionCRISPR CAS9 technology.png |
English: CRISPR Cas9 system has been successfully harnessed for mammalian genome editing. SpCas9 endonuclease uses the single guide RNA to find a specific target sequence to introduce double-strand break. Then, the cell introduces a mutation at the site of the break through the repair mechanisms of damaged DNA.
Русский: CRISPR Cas9 система успешно используется для направленного редактирования генома млекопитающих. Эндонуклеаза SpCas9 с помощью направляющей РНК находит точное место в геноме, чтобы внести двухцепочечный разрыв. Затем клетка вносит мутацию в месте внесенного разрыва с помощью механизмов репарации поврежденной ДНК. English: CRISPR/Cas9 genome editing technology. Three-dimensional structure of spCas9 ID 5Y36 from the Protein Data Bank (PDB) database. Structural image was prepared with the PyMOL Molecular Graphics System, Version 2.0 Schrödinger, LLC and Adobe Illustrator. |
Date | |
Source | Own work |
Author | Elena I Leonova |
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[edit]I, the copyright holder of this work, hereby publish it under the following license:
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 21:13, 28 March 2020 | 2,920 × 1,508 (1.81 MB) | Elena I Leonova (talk | contribs) | Uploaded own work with UploadWizard |
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