File:Bar plot of average number of de novo mutations by chromosome.jpg
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[edit]DescriptionBar plot of average number of de novo mutations by chromosome.jpg |
English: Bar plot of average number of de novo mutations by chromosome. The average number of de novo point mutations (DNMs) in each autosome are largely correlated with the chromosome sizes. The error bars represent the s.e. (standard error) of the mean DNMs for each chromosome. Numbers of DNMs in chromosomes 17, 19, 20, 21 and 22 are not significant for either father’s or mother’s age (P>0.05). Numbers of DNMs in chromosomes 1–4, 6, 8–15 and 18 are significantly correlated with father’s age only. Numbers of DNMs in chromosomes 5, 7, 16 are significantly correlated with both parents’ ages.
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Date | Published 19 January 2016 |
Source | Wong, W. S. W. et al. New observations on maternal age effect on germline de novo mutations. Nat. Commun. 7:10486 doi: 10.1038/ncomms10486 (2016). http://www.nature.com/ncomms/2016/160119/ncomms10486/full/ncomms10486.html |
Author | Wendy S. W. Wong, Benjamin D. Solomon, Dale L. Bodian, Prachi Kothiyal, Greg Eley, Kathi C. Huddleston, Robin Baker, Dzung C. Thach, Ramaswamy K. Iyer, Joseph G. Vockley & John E. Niederhuber |
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current | 07:42, 22 September 2016 | 946 × 1,096 (109 KB) | Was a bee (talk | contribs) | {{Information |Description={{en|1=Bar plot of average number of de novo mutations by chromosome. The average number of de novo point mutations (DNMs) in each autosome are largely correlated with the chromosome sizes. The error bars represent the s.e. (... |
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The following 3 pages use this file:
- File:Distribution of the ratios between number of DNMs of maternal origin and paternal origin.png
- File:Histograms of Age of Father, Mother and Newborn - Coloring with Number of mutations.png
- File:Scatter plots with linear regression line on parental ages and their respective number of de novo mutations.jpg
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