File:Auto-inhibition of Kinesin 1 from Drosophila Melanogaster.gif

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Auto-inhibition_of_Kinesin_1_from_Drosophila_Melanogaster.gif ‎(700 × 436 pixels, file size: 2.04 MB, MIME type: image/gif, looped, 30 frames, 12 s)

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English: Open Conformation: The positively charged IAK region of the tail (blue) is not present and therefore kinesin motor domains (yellow and orange) can move freely along the microtubule (MT). Closed Conformation: The IAK region of the tail (blue) hydrogen bonds at two locations with negatively charged residues (red) of the kinesin motor domains (yellow and orange) to inhibit the enzymatic cycle of the kinesin-1, forcing the molecular motor to maintain a closed conformation which prevents binding to the MT.
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Author Kaden.Rawson

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Date/TimeThumbnailDimensionsUserComment
current03:17, 23 April 2019Thumbnail for version as of 03:17, 23 April 2019700 × 436 (2.04 MB)Kaden.Rawson (talk | contribs)Cross-wiki upload from en.wikipedia.org

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