File:American journal of physiology (1898) (14781750985).jpg

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Identifier: americanjourna06ameruoft (find matches)
Title: American journal of physiology
Year: 1898 (1890s)
Authors: American Physiological Society (1887- ) American Physiological Society (1887- ). Abstracts of papers presented at the fall meeting American Physiological Society (1887- ). Proceedings
Subjects: Physiology Physiology
Publisher: (Bethesda, Md., etc.) American Physiological Society (etc.)
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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the presence of a larger or smaller amount of proteidimpurity.^ We can no longer believe that proteid impurity is responsible forthe observed variations. In the first place the quantity of solubleproteid in tendon, other than mucoid, is very slight. Experimentsin progress in this laboratory indicate that it is less than 0.3 percent. If, however, it were possible for all of this small quantity tocombine permanently with the precipitated mucoids, it could not ac-count for the regular rise and fall of nitrogen content observed ineach series of our experiments.^ Although it is conceivable that themucoid of the first extract could be so affected, such an assumptionwould not explain the rise of nitrogen in the third and subsequentextracts, particularly in view of the marked fall of the same in thesecond. Then, too, each product was so thoroughly washed in excess 1 See table on page i6i. - Chittenden and Gies: Loc. cit., p. 194. 2 See the table on page 162. .68 Ctitter an d Willia^^ / G^^^-
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The Composition of Tendo7t Mucoid 169 of 0.2 per cent hydrochloric acid, that unless very intimate and unusualchemical union resulted, lymph proteids must have been quickly andcompletely dissolved from the precipitates. We know of no othersubstance in tendon which would resist the washing treatment and,by mechanical admixture or chemical combination, account for theorderly variations observed in the analytic series.^ It is much more probable, we think, that an answer to these con-siderations will be found in the fact that the mucoids are labile bodiesof great variety in the tissues and with more than one function toperform. Their acid radicles doubtless make them prone to enterinto numerous ion combinations. The very complexity of these sub-stances makes it natural to assume that exactly the same proportionsof the constituent radicles would in metabolic changes be the excep-tion rather than the rule. All of the products separated in these experiments were true gluco-proteids, respondi

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American Physiological Society (1887- ); American Physiological Society (1887- ). Abstracts of papers presented at the fall meeting;

American Physiological Society (1887- ). Proceedings
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06
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30 July 2014



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