File:Aberrant-Expression-of-Interleukin-1β-and-Inflammasome-Activation-in-Human-Malignant-Gliomas-pone.0103432.g002.jpg
Aberrant-Expression-of-Interleukin-1β-and-Inflammasome-Activation-in-Human-Malignant-Gliomas-pone.0103432.g002.jpg (688 × 568 pixels, file size: 70 KB, MIME type: image/jpeg)
Captions
Captions
Summary
[edit]DescriptionAberrant-Expression-of-Interleukin-1β-and-Inflammasome-Activation-in-Human-Malignant-Gliomas-pone.0103432.g002.jpg |
English: Three patient-derived glioma cell lines (one low grade astrocytoma and two GBM cells) were tested for IL-1 protein production spontaneously (Ctr) and following IL-1/IFNγ stimulation. ELISA was performed with cell lysates (intracellular = i.c.) and culture supernatants (secreted = s). (A) IL-1 protein production was seen in GBM cells only. In one of them (GBM2), IL-1 production occurred spontaneously (Ctr) and was potentiated by IL-1 (± IFNγ). A portion of IL-1 was secreted. (B) Dose-dependent induction of IL-1: production of IL-1β was examined in GBM2 cells after stimulation with different concentrations (0.1 pg/ml to 100 ng/ml) of IL-1α. (C) IL-1β immunostain of unstimulated GBM2 cells reveals scattered positive cells, while preimmune IgG (negative control) showed no positive cells. Data shown are mean ± SD (n = 3), ***p<0.001, **p<0.01, *p<0.05 vs. control (Ctr). |
|
Date | ||
Source | Image file from Tarassishin L, Casper D, Lee S (2014). "Aberrant Expression of Interleukin-1β and Inflammasome Activation in Human Malignant Gliomas". PLOS ONE. DOI:10.1371/journal.pone.0103432. PMID 25054228. PMC: 4108401. | |
Author | Tarassishin L, Casper D, Lee S | |
Permission (Reusing this file) |
![]() ![]() This file is licensed under the Creative Commons Attribution 4.0 International license.
|
|
Provenance InfoField |
|
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 02:42, 25 July 2014 | ![]() | 688 × 568 (70 KB) | Recitation-bot (talk | contribs) | Automatic upload of media from: doi:10.1371/journal.pone.0103432 |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Image title |
|
---|---|
Publisher | Public Library of Science |
Short title |
|
Copyright holder |
|
Source | info:doi/10.1371/journal.pone.0103432 |
Date(s) | 23 July 2014 |
Identifier | info:doi/info:doi/10.1371/journal.pone.0103432.g002 |
IIM version | 2 |