File:A 670 nm red light photobiomodulation (PBM) reduces blood glucose levels.jpg

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From the study "Light stimulation of mitochondria reduces blood glucose levels"

Summary

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Description
English: "Exposure to 15 min of 670 nm light (n = 15), starting 45 min prior to oral glucose tolerance test (OGTT), significantly reduced blood glucose levels, from time point +45 min, compared with a placebo intervention (no light, n = 15). This was observed when the absolute blood glucose concentrations were compared (A) and confirmed by analysing each participants change in blood glucose from time point 0 min (B). Area under the curve analysis shows a 7.3% reduction in total circulating glucose concentration (C, p = 0.0061), and a 27.7% reduction in the post-glucose consumption rise in glucose levels (D, p = 0.0002) *p < 0.05, **p < 0.01, ***p < 0.005. Error bars are standard error of the mean. "

"OGTT data were similar over the first 30 min following glucose consumption in the 670 nm PBM and placebo groups irrespective of whether data were generated from absolute levels, or when baselined against time point 0 min (Figure 2A,B). Baselining data against time point 0 min reports deviation of blood glucose concentration following glucose consumption. When comparing the effect of a 670 nm PBM intervention against placebo in area under the curve, PBM reduced overall blood glucose concentrations by 7.3% (Figure 2C, p = 0.0061). In data from analysis baselined against their initial glucose measurement, the post-consumption elevation in blood glucose was reduced by 27.7% (Figure 2D, p = 0.0002)."

"A repeated measures ANOVA confirmed a significant difference in absolute blood glucose concentration (p = 0.035) and in the post-consumption elevation in glucose concentration from baselined data (p = 0.049). Post hoc analysis highlighted significant decreases in both measures at time points of 45-, 60-, 75-, and 90-min post-loading (Figure 2A,B)."

"In the 670 nm PBM group, immediately following initial blood glucose measurement, participants exposed an 800 cm2 region of upper back to 670 nm light for 15 min at an intensity of 40 mW cm−2 (28 800 J). This would illuminate skin cells and underlying musculature including the trapezius [23]. Light was delivered via light emitting diodes (LED); 670 nm peak wavelength with a half power band of ~10 nm (Light Power Health, UK). The LED array was positioned 400 mm from the participants back"
Date
Source https://onlinelibrary.wiley.com/doi/10.1002/jbio.202300521
Author Authors of the study: Michael B. Powner, Glen Jeffery

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