File:AT-121 synthesis.svg
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[edit]DescriptionAT-121 synthesis.svg |
English: Synthesis of AT-121, an opioid agonist, accoding to (2018). "A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates". Science Translational Medicine 10 (456): eaar3483. DOI:10.1126/scitranslmed.aar3483. PMID 30158150.. The synthesis of the first compound is described in (2008). "Synthesis and Pharmacological Evaluation of 1,2-Dihydrospiro[isoquinoline-4(3H),4′-piperidin]-3-ones as Nociceptin Receptor Agonists". Journal of Medicinal Chemistry 51 (4): 1058–1062. DOI:10.1021/jm7009606. PMID 18232652.. |
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Author | Hbf878 |
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This file is made available under the Creative Commons CC0 1.0 Universal Public Domain Dedication. | |
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http://creativecommons.org/publicdomain/zero/1.0/deed.enCC0Creative Commons Zero, Public Domain Dedicationfalsefalse |
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current | 21:33, 3 September 2018 | 512 × 328 (40 KB) | Hbf878 (talk | contribs) | Objects converted to paths. | |
21:33, 3 September 2018 | 512 × 328 (29 KB) | Hbf878 (talk | contribs) | User created page with UploadWizard |
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