File:A-dynamin-1--dynamin-3--and-clathrin-independent-pathway-of-synaptic-vesicle-recycling-mediated-by-elife01621f012.jpg

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A-dynamin-1--dynamin-3--and-clathrin-independent-pathway-of-synaptic-vesicle-recycling-mediated-by-elife01621f012.jpg ‎(734 × 576 pixels, file size: 144 KB, MIME type: image/jpeg)

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English: Ultrastructure of Dyn1/3 DKO neurons preincubated overnight in TTX, stimulated with high K+ for 90 s in the presence of soluble HRP and then allowed to recover for 60 min in HRP-free medium. (A) Representative EM micrographs and (B) quantification of the results showing that recovery of SVs after 1 hr is similar in controls and in the presence of BFA (25 μg/ml) or Lat. B (5 μM), though a modest statistical significance was found for total SVs recovery in BFA-treated neurons and HRP-labeled SVs in Lat.B treated conditions. SVs positive for HRP reaction product are indicated by the dark portion of each bar. Scale bar = 200 nm. *p<0.05, n.s., ‘not significant’. Black asterisks refer to comparisons between total vesicles, colored asterisks to comparisons between HRP-labeled vesicles. Bars: standard error of the mean.
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Source Image file from Wu Y, O'Toole E, Girard M, Ritter B, Messa M, Liu X, McPherson P, Ferguson S, De Camilli P (2014). "A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis". eLife. DOI:10.7554/eLife.01621. PMID 24963135. PMC: 4107917.
Author Wu Y, O'Toole E, Girard M, Ritter B, Messa M, Liu X, McPherson P, Ferguson S, De Camilli P
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current22:36, 30 September 2014Thumbnail for version as of 22:36, 30 September 2014734 × 576 (144 KB)Recitation-bot (talk | contribs)Automatic upload of media from: doi:10.7554/eLife.01621

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