File:13311 2018 674 Fig3 HTML (1)-Photoroom.jpg
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[edit]Description13311 2018 674 Fig3 HTML (1)-Photoroom.jpg |
English: Routes to treatment. Schematic depicts the mitochondrial targets of treatments currently being tested for use in treating mitochondrial myopathy. A wide range of approaches are currently in use including the targeting of mitochondrial biogenesis (bezafibrate, RTA-408, exercise, acipimox and nicotinamide riboside), oxidative phosphorylation (CoQ10, idebenone, riboflavin and thiamine), ROS (RTA-498, KH176, CoQ10, idebenone), increasing NAD+ (acipimox and nicotinamide riboside), mtDNA gene editing (mitochondrial TALENS and zinc finger nucleases), lipid utilization (ketogenic diet), and cardiolipin stabilization (elamipretide) |
Date | |
Source | https://link.springer.com/article/10.1007/s13311-018-00674-4 |
Author | Syeda T. Ahmed, Lyndsey Craven, Oliver M. Russell, Doug M. Turnbull & Amy E. Vincent |
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current | 22:05, 13 April 2024 | 685 × 400 (39 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Syeda T. Ahmed, Lyndsey Craven, Oliver M. Russell, Doug M. Turnbull & Amy E. Vincent from https://link.springer.com/article/10.1007/s13311-018-00674-4 with UploadWizard |
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